Warfarin Dosing in Patients With Impaired Kidney Function

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Warfarin dosing in patients with impaired kidney function.

BACKGROUND In patients with kidney impairment, warfarin, a drug metabolized primarily by the cytochrome P-450 system, is initiated at similar doses and managed similarly as in the general medical population. Unfortunately, few data exist to guide dose adjustment in patients with decreased kidney function. Here, we determine the degree of warfarin dose reduction associated with kidney impairment...

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Development and Comparison of Warfarin Dosing Algorithms in Stroke Patients.

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ژورنال

عنوان ژورنال: American Journal of Kidney Diseases

سال: 2010

ISSN: 0272-6386

DOI: 10.1053/j.ajkd.2010.05.023